Senior Data Scientist, AI Retrieval Systems
Axle · Remote · posted Aug 26, 2026
seniorhealthtech
What this role actually asks for
Extracted by RemoteHuntMust have
- •MS or PhD in Computer Science or related field
- •5+ years of experience in data science
- •Experience with large language models (LLMs)
- •Experience with retrieval augmented generation (RAG)
- •Experience with Python and SQL
- •Experience with Kubernetes and Helm
Nice to have
- •Experience with cloud platforms (AWS, Azure, GCP)
- •Experience with CI/CD pipelines
Tools and technologies
PythonSQLKubernetesHelm
The full posting
<div style="font-size: 10pt; font-family: 'Tahoma';">(ID: 2026-3395) <p> </p> <br> <p><strong>Axle</strong> is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).</p> </div> <p> </p> <div style="font-size: 10pt; font-family: 'Tahoma';"> <p><strong>Benefits We Offer:</strong></p> <ul> <li>100% Medical, Dental & Vision Coverage for Employees</li> <li>Paid Time Off and Paid Holidays</li> <li>401K match up to 5%</li> <li>Educational Benefits for Career Growth</li> <li>Employee Referral Bonus</li> <li>Flexible Spending Accounts: <ul> <li>Healthcare (FSA)</li> <li>Parking Reimbursement Account (PRK)</li> <li>Dependent Care Assistant Program (DCAP)</li> <li>Transportation Reimbursement Account (TRN)</li> </ul> </li> </ul> <p><span class="TextRun SCXW234214891 BCX8" lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW234214891 BCX8" data-ccp-parastyle="First Paragraph" data-ccp-parastyle-defn="{"ObjectId":"276295ed-5df2-5456-988c-5fdbab071054|1","ClassId":1073872969,"Properties":[469777841,"Charter",469777844,"Charter",469769226,"Charter",268442635,"21",201342446,"1",201342447,"5",201342448,"3",201342449,"1",469777842,"",469777843,"",201341986,"1",335559739,"180",335559738,"180",469775450,"First Paragraph",201340122,"2",134234082,"true",134233614,"true",469778129,"FirstParagraph",335572020,"1",469775498,"Body Text",469778324,"Body Text"]}">Axle is seeking a Senior Data Scientist, AI Retrieval Systems to join our vibrant team supporting rare disease research at the National Institutes of Health (NIH). This is a Remote position within the United States.</span></span><span class="EOP Selected SCXW234214891 BCX8" data-ccp-props="{"335559738":180,"335559739":180}"> </span></p> </div> <div class="ck-content" style="font-family: Segoe UI; font-size: 11pt;" data-wrapper="true"> <div class="SCXW247496889 BCX8" style="background-color: rgb(255, 255, 255); color: rgb(0, 0, 0); font-family: 'Segoe UI', 'Segoe UI Web', Arial, Verdana, sans-serif; font-size: 12px; font-style: normal; font-weight: 400; letter-spacing: normal; margin: 0px; padding: 0px; text-align: start; white-space: pre-wrap; word-spacing: 0px;"> <div class="OutlineElement Ltr SCXW247496889 BCX8" style="clear: both; margin: 0px; overflow: visible; padding: 0px; position: relative;"> <p class="Paragraph SCXW247496889 BCX8" style="background-color: transparent; color: rgb(14, 90, 99); font-style: normal; font-weight: bold; margin: 10.6667px 0px 5.33333px; padding: 0px; text-align: left; vertical-align: baseline;"><span style="color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="TextRun SCXW247496889 BCX8 NormalTextRun BookmarkStart BookmarkEnd" lang="EN-US" style="font-weight: bold; line-height: 20.5042px; margin: 0px; padding: 0px;" data-contrast="none" data-ccp-parastyle="heading 2">Position Summary:</span></span></p> </div> <div class="OutlineElement Ltr SCXW247496889 BCX8" style="clear: both; margin: 0px; overflow: visible; padding: 0px; position: relative;"> <p class="Paragraph SCXW247496889 BCX8" style="background-color: transparent; color: windowtext; font-style: normal; font-weight: normal; margin: 12px 0px; padding: 0px; text-align: left; vertical-align: baseline;"><span style="color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="First Paragraph" data-ccp-parastyle-defn="{"ObjectId":"276295ed-5df2-5456-988c-5fdbab071054|1","ClassId":1073872969,"Properties":[469777841,"Charter",469777844,"Charter",469769226,"Charter",268442635,"21",201342446,"1",201342447,"5",201342448,"3",201342449,"1",469777842,"",469777843,"",201341986,"1",335559739,"180",335559738,"180",469775450,"First Paragraph",201340122,"2",134234082,"true",134233614,"true",469778129,"FirstParagraph",335572020,"1",469775498,"Body Text",469778324,"Body Text"]}">Roughly 25</span><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="First Paragraph"> to 30 million people in the United States live with a rare disease. There are somewhere between 7,000 and 10,000 distinct rare conditions, and the large majority have no FDA-approved treatment.</span></span><span style="background-color: rgb(198,198,198)!important; color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="EOP Selected SCXW247496889 BCX8" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-ccp-props="{"335559738":180,"335559739":180}"> </span></span></p> </div> <div class="OutlineElement Ltr SCXW247496889 BCX8" style="clear: both; margin: 0px; overflow: visible; padding: 0px; position: relative;"> <p class="Paragraph SCXW247496889 BCX8" style="background-color: transparent; color: windowtext; font-style: normal; font-weight: normal; margin: 12px 0px; padding: 0px; text-align: left; vertical-align: baseline;"><span style="color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Body Text">Research on these conditions keeps running into the same obstacles. Published evidence for any one disease is thin and scattered across sources. The same clinical finding gets written down a dozen different ways depending on who recorded it. And the people with the most at stake, patients and their families, are usually the least equipped to read </span><span class="TextRun SCXW247496889 BCX8 NormalTextRun ContextualSpellingAndGrammarErrorV2Themed" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Body Text">the specialist</span><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Body Text"> literature written about their own condition.</span></span><span style="background-color: rgb(198,198,198)!important; color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="EOP Selected SCXW247496889 BCX8" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-ccp-props="{"335559738":180,"335559739":180}"> </span></span></p> </div> <div class="OutlineElement Ltr SCXW247496889 BCX8" style="clear: both; margin: 0px; overflow: visible; padding: 0px; position: relative;"> <p class="Paragraph SCXW247496889 BCX8" style="background-color: transparent; color: windowtext; font-style: normal; font-weight: normal; margin: 12px 0px; padding: 0px; text-align: left; vertical-align: baseline;"><span style="color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Body Text">Large language models are well suited to this class of problem, and the research programs we support are investing in applying them carefully. In this role you will build the retrieval and knowledge layer that those AI systems stand on. That means the disease and phenotype vocabularies that give a model something precise to reason over, the semantic search that finds the right concept behind an imprecise human phrase, and the ranking that decides what a user sees first. Ontologies serve as internal scaffolding throughout. Users should never have to see one or learn what it is.</span></span><span style="background-color: rgb(198,198,198)!important; color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="EOP Selected SCXW247496889 BCX8" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-ccp-props="{"335559738":180,"335559739":180}"> </span></span></p> </div> <div class="OutlineElement Ltr SCXW247496889 BCX8" style="clear: both; margin: 0px; overflow: visible; padding: 0px; position: relative;"> <p class="Paragraph SCXW247496889 BCX8" style="background-color: transparent; color: windowtext; font-style: normal; font-weight: normal; margin: 12px 0px; padding: 0px; text-align: left; vertical-align: baseline;"><span style="color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Body Text">This is a senior individual contributor position with </span><span class="TextRun SCXW247496889 BCX8 NormalTextRun ContextualSpellingAndGrammarErrorV2Themed" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Body Text">unusual</span><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Body Text"> range. You will own the data layer, the retrieval services built on top of it, the interfaces where results become visible, and the path onto the computing infrastructure that runs it all. You will work directly with NIH program staff, clinical geneticists, and rare disease information specialists.</span></span><span style="background-color: rgb(198,198,198)!important; color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="EOP Selected SCXW247496889 BCX8" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-ccp-props="{"335559738":180,"335559739":180}"> </span></span></p> </div> <div class="OutlineElement Ltr SCXW247496889 BCX8" style="clear: both; margin: 0px; overflow: visible; padding: 0px; position: relative;"> <p class="Paragraph SCXW247496889 BCX8" style="background-color: transparent; color: rgb(14, 90, 99); font-style: normal; font-weight: bold; margin: 10.6667px 0px 5.33333px; padding: 0px; text-align: left; vertical-align: baseline;"><span style="color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="TextRun SCXW247496889 BCX8 NormalTextRun BookmarkStart BookmarkEnd" lang="EN-US" style="font-weight: bold; line-height: 20.5042px; margin: 0px; padding: 0px;" data-contrast="none" data-ccp-parastyle="heading 2">Core Responsibilities:</span></span></p> </div> <div class="ListContainerWrapper SCXW247496889 BCX8" style="margin: 0px; padding: 0px; position: relative;"> <ul> <li class="ck-list-marker-font-size ck-list-marker-color ck-list-marker-font-family" data-list-item-id="eb0c80996781fac2f15206dc1f2ebd8a8"> <p class="Paragraph SCXW247496889 BCX8" style="background-color: transparent; color: windowtext; font-style: normal; font-weight: normal; margin: 0px; padding: 0px; text-align: left; vertical-align: baseline;"><span style="color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact" data-ccp-parastyle-defn="{"ObjectId":"eafb41c0-47a4-52dc-ac6b-3b5a7536b560|1","ClassId":1073872969,"Properties":[469777841,"Charter",469777844,"Charter",469769226,"Charter",268442635,"21",201342446,"1",201342447,"5",201342448,"3",201342449,"1",469777842,"",469777843,"",201341986,"1",335559739,"36",335559738,"36",469775450,"Compact",201340122,"2",134234082,"true",134233614,"true",469778129,"Compact",335572020,"1",469778324,"Body Text"]}">Model biomedical knowledge for rare disease research. Ingest disease and phenotype ontologies and controlled vocabularies into PostgreSQL with a maintainable release and refresh path, reconcile identifiers across sources, and work through term hierarchies to </span><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact">determine what is clinically relevant for a given condition.</span></span><span style="background-color: rgb(198,198,198)!important; color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="EOP Selected SCXW247496889 BCX8" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-ccp-props="{"335559738":36,"335559739":36}"> </span></span></p> </li> </ul> </div> <div class="ListContainerWrapper SCXW247496889 BCX8" style="margin: 0px; padding: 0px; position: relative;"> <ul> <li class="ck-list-marker-font-size ck-list-marker-color ck-list-marker-font-family" data-list-item-id="e4c121976d326caa5602c5ec30173f1bf"> <p class="Paragraph SCXW247496889 BCX8" style="background-color: transparent; color: windowtext; font-style: normal; font-weight: normal; margin: 0px; padding: 0px; text-align: left; vertical-align: baseline;"><span style="color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact">Build retrieval-augmented services that ground everyday language in clinical concepts. Embed term labels, definitions, and synonyms, retrieve candidates, and have a model </span><span class="TextRun SCXW247496889 BCX8 NormalTextRun ContextualSpellingAndGrammarErrorV2Themed" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact">disambiguate</span><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact"> against context before any value is committed.</span></span></p> </li> </ul> </div> </div> <div class="SCXW247496889 BCX8" style="background-color: rgb(255, 255, 255); color: rgb(0, 0, 0); font-family: 'Segoe UI', 'Segoe UI Web', Arial, Verdana, sans-serif; font-size: 12px; font-style: normal; font-weight: 400; letter-spacing: normal; margin: 0px; padding: 0px; text-align: start; white-space: pre-wrap; word-spacing: 0px;"> <div class="ListContainerWrapper SCXW247496889 BCX8" style="margin: 0px; padding: 0px; position: relative;"> <ul> <li class="ck-list-marker-font-size ck-list-marker-color ck-list-marker-font-family" data-list-item-id="e697cd4116bb24f56182b2b0dcce3abb6"> <p class="Paragraph SCXW247496889 BCX8" style="background-color: transparent; color: windowtext; font-style: normal; font-weight: normal; margin: 0px; padding: 0px; text-align: left; vertical-align: baseline;"><span style="color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact">Treat retrieval as a database problem. Tune keyword and vector search over large biomedical </span><span class="TextRun SCXW247496889 BCX8 NormalTextRun ContextualSpellingAndGrammarErrorV2Themed" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact">corpora, and</span><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact"> be ready to defend the recall and latency trade-offs you choose.</span></span></p> </li> </ul> </div> <div class="ListContainerWrapper SCXW247496889 BCX8" style="margin: 0px; padding: 0px; position: relative;"> <ul> <li class="ck-list-marker-font-size ck-list-marker-color ck-list-marker-font-family" data-list-item-id="e68f80dab378c131fdfedd56eb4296843"> <p class="Paragraph SCXW247496889 BCX8" style="background-color: transparent; color: windowtext; font-style: normal; font-weight: normal; margin: 0px; padding: 0px; text-align: left; vertical-align: baseline;"><span style="color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact">Build the ranking and relevance layers that decide what surfaces first, including domain-aware weighting and graceful degradation when a condition falls outside curated coverage.</span></span></p> </li> </ul> </div> <div class="ListContainerWrapper SCXW247496889 BCX8" style="margin: 0px; padding: 0px; position: relative;"> <ul> <li class="ck-list-marker-font-size ck-list-marker-color ck-list-marker-font-family" data-list-item-id="e209a8501a99ac6abea0b962996ab5f13"> <p class="Paragraph SCXW247496889 BCX8" style="background-color: transparent; color: windowtext; font-style: normal; font-weight: normal; margin: 0px; padding: 0px; text-align: left; vertical-align: baseline;"><span style="color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact">Deliver the interfaces where this work becomes visible to users, in Next.js, React, and TypeScript. This covers question and </span><span class="TextRun SCXW247496889 BCX8 NormalTextRun ContextualSpellingAndGrammarErrorV2Themed" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact">confirmation</span><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact"> flows, result presentation, and live status for long-running pipelines.</span></span></p> </li> </ul> </div> <div class="ListContainerWrapper SCXW247496889 BCX8" style="margin: 0px; padding: 0px; position: relative;"> <ul> <li class="ck-list-marker-font-size ck-list-marker-color ck-list-marker-font-family" data-list-item-id="e822ace504434082349fa0e9a4359192d"> <p class="Paragraph SCXW247496889 BCX8" style="background-color: transparent; color: windowtext; font-style: normal; font-weight: normal; margin: 0px; padding: 0px; text-align: left; vertical-align: baseline;"><span style="color: #000000; font-family: Tahoma; font-size: 10pt;"><span class="TextRun SCXW247496889 BCX8 NormalTextRun" lang="EN-US" style="line-height: 17.2667px; margin: 0px; padding: 0px;" data-contrast="auto" data-ccp-parastyle="Compact">Deploy continuously onto NIH on-premises and high-performance computing Kubernetes environments. Helm charts, </span><span class="TextRun SCXW247496889 BCX8 NormalTextRun SpellingErrorV2Themed" lang="EN-US" style="line-height: 17.2667px; margin: 0px; p
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